A 77-year-old man presented with a 1-year history of upper limb rest tremor, rigidity, and bradykinesia. He reported focal dystonia affecting the right thumb over the preceding 7 years, resulting in a constant "thumbs up" gesture reminiscent of the fictional television character Arthur Fonzarelli. Subsequent levodopa therapy reduced his bradykinesia and rigidity, but did not ameliorate the dystonia.
While foot dystonia is a common feature in late Parkinson disease (PD), dystonia may precede the development of PD by several years. Writer's cramp has been described as an early manifestation, with extension of the great toe also noted (the striatal foot).
So long as we've started a toilet thread, let's all watch "Color It Clean," so that we appreciate the men and women who maintain our public lavatories.
This film reminds me of Barney Gumble's autobiographical entry in the Springfield Film Festival. I could find the clip only in Italian, but that adds a certain frisson to the viewing experience, I think.
So far as I can tell, the tiger stalking Galveston is still on the loose. But the Galvestonians could have it much worse. Consider the plight of the citizens of the Sundarbans in India.
I first learned of the reign of man-eating tigers here ten years ago, watching this series of PBS's NATURE show. One episode revealed how the natives had to wear human face masks on the backs of their heads to avoid tigers pouncing on them and eating them. (It was not a totally successful tactic.) I believe this bit later showed up in the wonderful Calvin and Hobbes strip, with Calvin trying the same tactic to avoid Hobbes's attacks.
Well, the tigers of Sundarbans continue to feast on human flesh, as we learn in this new report. Read, and be happy no tigers roam your city's streets.
SURGEON GENERAL'S WARNING: Ingesting almost two hours of vintage cigarette commercials for the same brand might be dangerous to your health. Symptoms may include light-headedness, uncontrollable giggling, and a desire to stick two cigarettes in your mouth simultaneously. Indulge with caution!
In this NEW YORK TIMES article from today, scientists reveal their latest findings about which brain cells are excited during the recall of memories, and how closely memory tallies with literally re-enacting the events. And they use a tantalizing example:
After briefly distracting the patients, the researchers then asked them to think about the clips for a minute and to report “what comes to mind.” The patients remembered almost all of the clips. And when they recalled a specific one — say, a clip of Homer Simpson — the same cells that had been active during the Homer clip reignited. In fact, the cells became active a second or two before people were conscious of the memory, which signaled to researchers the memory to come.
Why is Homer Simpson singled out as the test case? Obviously because the human brain has specific neurons that emulate or actually induce and compel Homer-Simpson-style behavior.
And there in a nutshell you have the whole basis for ninety-nine percent of the contents of WEIRD UNIVERSE.
Category: Medicine, Science, Television